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Studies have found that GLP-1R is widely distributed on pancreatic and other tissues and has multiple biological effects, such as reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism and reducing fat deposition
& Burster, T
At present, the effects of incretin combination therapies on weight loss are approaching those of bariatric surgery, marking the advent of a new era in pharmacological treatment for obesity
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