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suspected reactions should be reported via the MHRA Yellow Card scheme
Contact dermatitis (redness, irritation, itchiness, rashes) is the most common side effect, especially for sensitive skin
Both drugs substantially reduced lifetime incidences of obesity, diabetes, and CVDpreventing up to 45,609 obesity and 20,854 diabetes cases per 100,000 individualsand yielded the largest incremental Quality-Adjusted Life Year (QALY) gains (0.35 for tirzepatide
Using the right methods and schedules is important for success
Some women with polycystic ovary syndrome (PCOS) have reported improved menstrual regularity whilst taking GLP-1 medications, though this is likely related to weight loss and improved insulin sensitivity rather than a direct pharmacological effect on ovarian function
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