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Presented for research literature review only Raney KD et al
The novel arsenical darinaparsin is transported by cystine importing systems
To assess whether the level of ER stress, which is often coupled to mitochondrial dysfunction 34 , may be impacted by colistin treatment and rescued by co-incubation with L-carnitine, a staining against the ER stress marker GRP78/BiP was conducted
it could be reduced within the ER by a glutathione reductase, it could be transported to the cytosol for reduction, or it could be secreted from the cell
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