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In practice, simultaneous application is problematic: a 2022 Journal of Cosmetic Dermatology study found that applying both at the same time increased transepidermal water loss by 41% and produced 3.2 times more self-reported stinging compared to staggered application
These medications produce 15-21% average body weight reduction in clinical trials numbers that were unthinkable from pharmacotherapy even five years ago
Pharmaceutics 15, 2229
The Hosmer and Lemeshow test was not significant ( X 2 (8) = 3.96, p = 0.86), indicating the model was a good fit for the data
This isnt enough support for a medication this powerful or for a goal as personal as weight loss because weight loss journeys arent linear
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