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In addition, the British National Formulary offers the following advice: Important: When prescribing an antipsychotic for administration on an emergency basis, the intramuscular dose should be lower than the corresponding oral dose (owing to absence of first-pass effect), particularly if the patient is very active (increased blood flow to muscle considerably increases the rate of absorption)

HPLC Chromatogram of the standard mixture of the major components in Hitrechol (a) and Hitrechol capsules (b)

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doi: 10.1136/ard.58.2008.i121 92 HuberAKIraniDN

Brown NC, Andreazza AC, Young LT (2014) An updated meta-analysis of oxidative stress markers in bipolar disorder