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During acute hypoxia, adenosine triphosphate (ATP) binds to hemoglobin, lowering its oxygen affinity to promote oxygen release to peripheral tissues
More capillaries mean better nutrient delivery and waste removal, supporting all aspects of tissue repair
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Transl Psychiatry 11 , 204 (2021)
We therefore propose that tissue-associated oxidative stress may promote conversion of circulating TTR into dsNNTTR locally within the interstitial compartment, rather than exclusively during intracellular synthesis or processing
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