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It was first isolated from human plasma in the 1970s by Dr
The slides were mounted with a solution containing DAPI (Molecular Probes) and imaged using a Leica TCS SP8 laser scanning confocal microscope (Leica Microsystems CMS GmbH, Wetzlar, Germany)
In this process, the increased expression of hypoxia-inducible factor 1 (HIF-1) is a pivotal hallmark
Following the generation of synaptic and action potentials, neurons use ATP released by glutamate to restore ion gradients, creating a metabolic signal that elevates CBF to meet energy requirements [86]
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