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Which Looks Stronger
In this article we compare mechanisms, dosing, outcomes, and real-world considerations so you can decide whether a clinician-supervised GLP-1 program is right for you
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Finally, while the primary outcomes we selected (weight loss and HbA1c) were consistent with clinical trial endpoints, they are limited in their ability to analyze early and true physiological impacts of GLP-1s such as changes to visceral and subcutaneous fat
Chronic inflammation, mitochondrial dysfunction, oxidative stress, changes in the extracellular matrix such as increased collagen deposition [26], vascular dysfunction and neurohormonal changes have all been linked to the development of sarcopenia [1, 17, 27, 28]
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