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Some factors that influence how long the shot lasts include: Lifestyle and stress levels Diet and alcohol consumption Existing health conditions (e.g., pernicious anemia, digestive disorders) How quickly your body uses or excretes B12 If your energy starts fading or symptoms return before your next scheduled shot, let your provider know

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If you have an underlying health condition like kidney disease, or if you take medication that interferes with B6 metabolism or absorption (such as oral contraceptives, hypertension drugs like hydralazine, and others), ask your doctor about appropriate supplement dosing

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