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Chronic administration of exenatide increases cell replication, reduces apoptosis and cellular stress, and increases insulin sensitivity in a nonhuman primate [25]
Whilst GLP-1 receptor activation can exert multiple direct neuroprotective effects, the protective influence of GLP-1 receptor agonists may occur indirectly through the restoration of the dysfunctional insulin signaling associated with neurodegenerative disease
Bellomo noted that these dynamics may affect insurers in multiple ways: Improved health could reduce life insurance claims, while longer lifespans may increase demand for retirement income products such as annuities
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