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Clinical use and practical aspects Patients who need further intensification of therapy but have had it delayed because of concerns about potential weight gain and hypoglycemic episodes would probably benefit from fixed-ratio combination of basal insulin and GLP-1Ras [19, 22, 23, 25,26,27, 30, 31]
Meet the experts: Kunal Shah, MD, is an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center
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Individual tolerance requires monitoring during the first weeks of treatment, starting at lower doses to establish your personal response pattern