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doi: 10.1038/s41423-025-01278-7 91 HidalgoALibbyPSoehnleinOAramburuIVPapayannopoulosVSilvestre-RoigC

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Current evidence indicates that cuproptosis can occur in structural cells such as epithelial cells, endothelial cells, and fibroblasts, and may also affect certain T cell and macrophage populations, with its impact on cytokine profiles and immune metabolic states being more indirectly regulated through mitochondrial function and metabolic reprogramming (132)

BPC-157 and TB-500 remain chemically distinct components within the lyophilized preparation and do not form covalent conjugates under standard manufacturing and storage conditions

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