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The research literature consistently describes DSIP as a sleep-promoting neuromodulator not a hypnotic or sedative agent with a modulating effect on sleep and wake functions that is most pronounced when sleep is disturbed, and minimal in healthy subjects without sleep disruption

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It is possible such a group may reduce alcohol consumption even without taking GLP-1s, when compared to a sample of the general population

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Inadequate Therapeutic Response: Contact your healthcare provider if you experience minimal or no improvement in target outcomes after reaching your maintenance dose for 12-16 weeks