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Although pharmacological compounds are being studied (Reference Khera, Murad and Chandar21) , natural compounds might be used to prevent the development of overweight- and obesity-related problems from early preclinical stages through interaction with the enteroendocrine system (Reference Serrano, Casanova-Mart and Blay22)
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These results (together with those in Figure 4D) suggest that HSV-1 promotes Ku80 post-translational modifications (e.g., ubiquitylation or sumoylation) and proteasomal degradation in infected neurons
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