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Injection into muscle tissue or blood vessels can alter drug absorption and increase the risk of adverse effects

Drug interactions happen when one medication affects how another works or increases the risk of adverse effects

This matters most in longitudinal or multi-cohort research, where a vial reconstituted three weeks ago and a freshly prepared vial from the same batch may behave differently in downstream results a discrepancy that is trivial to explain with a log and easy to misattribute to biological variance without one

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