Its levels decline naturally with age, and this decline is accelerated by chronic conditions including HIV/AIDS, cancer, type 2 diabetes, Parkinson's disease, and hepatitis
Specifically, these results suggest that they may reduce the immune response, under normal conditions, while enhancing its response to pathogens
Potential risks include hormone imbalances, effects on blood sugar levels, and increased IGF-1 (insulin-like growth factor) levels, which may lead to other risks over time
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The 20-30 hour half-life means the peptide still distributes systemically regardless of site, so any local-only effect is partial at best