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Laiteerapong N, Huang ES

Evidence strength varies considerably by indication, and most body composition claims in healthy adults rest on mechanistic reasoning and practitioner-reported experience rather than robust controlled human trials

In some embodiments, a formulation can include a dose of about 0.01-1.0 mg, about 0.1-1.0 mg, about 0.5-5.0 mg, about 1.0-5 mg, about 2.0-10mg, about 5.0-20 mg, about 5.0-30 mg, about 30-90 mg, about 70-90 mg, about 30-110 mg, about 70-110 mg, about 150-450 mg, or about 300-1200 mg of a therapeutic agent

Most commodity vendors do not meet all three criteria

The nasal spray formulation provides a standardized research format that supports consistency within experimental protocols and facilitates administration in controlled laboratory environments