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Notably, NDBs disrupt bacterial membranes instead of targeting specific metabolic pathways, a mechanism less prone to resistance development (Bustamante-Torres et al., 2022
Research suggests that its activity may be linked to VEGF and TGF- signaling, fibroblast activation, and endothelial function
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4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency
Compounded medications have not undergone the same review process as FDA-approved drugs and are not interchangeable with brand-name products
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