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The results reported that AngIV had a very short half life of less than 2 minutes, however, each of the N-terminal modified compounds, such as Dihexa, exhibited elongated half-lives in comparison to the parent compound
Nakagawa H, Inazawa J, Inoue K, Misawa S, Kashima K, Adachi H, Nakazato H, Abe T: Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16
Collagen and Fibroblast Activity It appears to enhance fibroblast migration and collagen organization, which are essential for tendon and ligament healing. 3
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