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Limits of the Evidence The main selectivity data came from rat cells, rats, and swine
HS induces S-sulfhydration of MuRF1 at the Cys44 site, inhibiting its E3 ligase activity, reducing SERCA2a ubiquitination and degradation, thereby restoring SERCA2a function, lowering intracellular Ca 2+ , and enhancing contractile performance (Peng et al., 2022)
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For verified compound data (formula, SMILES, CAS, salt-form notes, PubChem CID), see our 5-Amino-1MQ research overview
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