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In addition, loperamide was found to reduce TNF- levels and induce the production of antimicrobial peptides, such as bactericidal/permeability increasing protein and LL37, enhancing hosts ability to fight against M.tb infections while protecting tissues from excessive inflammatory damage [13]

After overnight incubation at 25 C, cells were collected and resuspended in 20 mL ice-cold lysis buffer (10 mM TrisHCl, pH 8.0, 150 mm NaCl, and 1 mM EDTA) and homogenized using an Aminco French press

2016;22 (Suppl 3):1-203

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