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A significant portion are people who play tennis or golf recreationally and have been dealing with tendon tears or chronic overuse injuries for months

WOMAC pain index reduction of 75.8%

While there is some existing research on berberine as a standalone supplement, the evidence doesn't support the idea that it works as effectively as a prescription GLP-1 medication , and studies on the transdermal delivery method (absorbing supplements through the skin) for these ingredients are lacking

10.1080/01635581.2017.1295090 140 WangJ.LiuX.QiuY.ShiY.CaiJ.WangB.et al (2018)

Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al