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Funding This work was supported by Novo Nordisk Farmacutica do Brasil LTDA
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In addition to an increase in mitochondrial cholesterol which further increases -amyloid, and tau induced toxicity (Ribas et al., 2014)
Red flag: Severe persistent nausea or vomiting after every meal
In preclinical studies, cotadutide demonstrated a more pronounced loss of body weight, reduction in food intake, and superior improvement in glycemic parameters in rodents compared to a GLP-1 RA
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