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Mice tolerated the treatment well throughout the study period

While effective, it can cause side effects ranging from mild to serious, including oral thrush, headaches, sore throat, hoarseness, and rare adrenal suppression

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This section presents current neuron-targeted therapeutic strategies, organized along a conceptual axis from extracellular modulation (e.g., receptor activation and trophic signaling) to intracellular mechanisms (e.g., signal transduction, transcriptional regulation and metabolic support)

That means when temperatures outside drop, your body must burn more fuel just to keep you warm