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Without an adequate insulin supply, glucose cant enter your cells, meaning more stays in your blood
The authors note that allodynia and dysesthesia have been previously reported as adverse reactions to semaglutide
Tirzepatide follows a similar pattern starting at 2.5 mg for 4 weeks, then 5 mg, then increasing by 2.5 mg increments every 4 weeks up to 15 mg
Titration, Monitoring & Protocol Adjustment Both semaglutide and tirzepatide require slow titration to minimize GI side effects and allow your body to adapt
Ji L, Dong X, Li Y et al (2021) Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as add-on to metformin in patients with type 2 diabetes in SUSTAIN China: a 30-week, double-blind, phase 3a, randomized trial
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