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Danish drugmaker Novo Nordisk said the Food and Drug Administration approved its once-a-week shot for people with Type 2 diabetes

All three contain semaglutide but differ in formulation and licensed indications: Ozempic is a weekly injection (up to 2.0 mg) licensed for type 2 diabetes, Wegovy is a weekly injection (2.4 mg) licensed specifically for weight management, and Rybelsus is a daily oral tablet (up to 14 mg) licensed only for type 2 diabetes

It can also precipitate withdrawal for those taking Suboxone (buprenorphine) or methadone

At Klinic in Tooele, Utah, semaglutide is tailored for individuals desiring sustainable weight loss

However, appetite suppression effects reverse after stopping GLP-1 medication, and the hormonal drivers of weight gain return