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Seizure and Stroke Experiments DSIP and analogues have been examined in induced seizure and experimental stroke models

Very large doses can result in lactic acidosis (a drop in pH of the blood) and coma (Ferner 2011

Kaiya et al., 2003

Category 2 designation means the substance presents "safety concerns" and is prohibited from being used in compounding by licensed pharmacies

This effect is irrespective of whether or not you have diabetes, as AMPK is involved in all of our tissues, and metformin offers broad-spectrum support against conditions like obesity, cancer, heart disease, and even neurodegenerative conditions