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Challenges: Despite their therapeutic benefits, GLP-1 receptor agonists face several limitations
Glutamine is needed to produce the neurotransmitter called glutamate
FIGURE 3 2.4.1 Terpenoids 2.4.1.1 -Elemene Studies have shown that -Elemene can directly bind to transcription factor EB (TFEB), a master modulator of lysosome activation, and stimulate its activation and nuclear translocation, which in turn leads to GPX4 lysosomal degradation in NSCLC
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