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Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

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In aged rat models, oral 5-amino-1mq capsules significantly improved myocardial mitochondrial function, reduced cardiomyocyte apoptosis, decreased myocardial injury markers (such as CK-MB, cTnI), enhanced cardiac contractility, and alleviated aging-related myocardial fibrosis

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Route Published human studies mainly used oral and intravenous forms