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Digestive Issues The most common side effects caused by GLP-1 drugs are those affecting the gastrointestinal tract: Nausea Vomiting Diarrhea Constipation Bloating They arise due to the slowing down of food transit from the stomach into the small intestine
Initial laboratory assessment should include a complete blood count and serum vitamin B 12 level
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Mitochondrial Respiration and Hypoxia Protection The 2003 study by Khvatova, Samartzev, Zagoskin, Prudchenko, and Mikhaleva published in Peptides confirmed that DSIP significantly increased ADP-stimulated mitochondrial respiration in rat brain mitochondria under experimental hypoxia conditions establishing a direct mitochondrial respiratory mechanism for DSIPs stress-protective potency and linking DSIP biology to the emerging field of mitochondria-targeted neuroprotective peptides
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