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Weight Loss Adherence (12 mo) Total Value Consideration GLP-1 (unmonitored) $10,000$13,000 1015% ~5060% dropout High drug waste GLP-1 (with monitoring) $10,000 + $60 (monitoring) 1015% ~75% persistence ROI-positive (saves $3k+ per patient) SGLT2 inhibitor $6,000$7,000 23% ~70% Lower cost, but modest outcomes Older anti-obesity meds $500$2,000 35% ~4050% Low efficacy, poor tolerability --- 3
Using patient reported outcomes in diabetes research and practice: recommendations from a national workshop
Similarly, the hemolytic profile of the designer peptides is also essential for assessing their biocompatibility and selectivity towards human erythrocytes
Gastric sleeve procedures produce 25-30% weight loss
Its available over-the-counter in 2% formulation (traditionally marketed to women) and 5% formulation (marketed to men but safe for women to use as well)
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