The prevention of steatohepatitis development is well-documented, as shown by the LEAN-J study, in which liraglutide attained histological resolution in 39% of patients, compared to 9% in the control group (Eguchi et al
Characterization of the GSTU10-10 isoenzyme revealed that it has an antioxidant catalytic function by acting as a hydroperoxidase and has a very low K m for GSH suggesting that GSTU10-10 is able to perform efficient catalysis under conditions where GSH concentrations are low, e.g., during oxidative stress (Skopelitou et al., 2015)
Coverage for people who are overweight or have obesity, however, is much less common
This matters in several specific research contexts
Mi X, Hammill BG, Curtis LH, Lai EC, Setoguchi S