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Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors

This leads to a faster breakdown of glutathione (GSH), a key antioxidant

Reduced shedding

found that pre-treatment with sulforaphane effectively abolished 6-OHDA and H 2 O 2 induced oxidative stress and cytotoxicity in a dopaminergic-like neuroblastoma SH-SY5Y cell line 24

During homeostasis, CAMs such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), and platelet/endothelial cell adhesion molecule-1 (PECAM-1), favor junctional stability and leukocyte surveillance [45]