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Gently massage it onto clean, damp skin in circular motions for 2 to 3 minutes, then rinse off with warm water

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Summary: Long-term calorie restriction doesnt appear to directly impact IGF-1 levels in humans, although it may make it less active

Mounjaro is typically prescribed for individuals with a BMI of 30 or higher (obesity), or a BMI of 27 or higher if accompanied by conditions like type 2 diabetes , high blood pressure, or high cholesterol

Metformin, in particular, is often maintained as foundational therapy due to its low cost, weight neutrality, and long-term clinical experience