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GLP-1 receptor agonists such as liraglutide, semaglutide, and dulaglutide have shown significant reductions in major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke, primarily in people with established cardiovascular disease or high cardiovascular risk

10.3389/fncel.2022.841731 72 WangY.CaoP.AlshwmiM.JiangN.XiaoZ.JiangF.et al (2019)

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That uncertainty is precisely why it remains an interesting research tool rather than a settled one, and it is stated plainly here rather than papered over with confident mechanism claims