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The median time (IQR) of ICU stay was 8 days (136) in the patients treated with NAC and was 10 days (176) in the patients treated with placebo, but this difference was not statistically significant ( p value = 0.48)
Several studies have shown that glutathione related enzymes like GSH S-transferase (GST) and GSSG reductase isoforms are not uniformly distributed in nuclei and cytoplasm [15]
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In many patients, it is a metabolic and cognitive risk amplifier
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