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It must be applied in a thin layer at night, on the face
[17] [18] During injection: Relax the muscles at the injection sitetension increases pain perception
Adverse effects Common: Increased risk of urinary infections, dizziness, urinary disorders, thirst, hypoglycaemia (when combined with insulin or sulfonylureas), skin reactions, genital infections
Men with diabetes respond to PDE-5 inhibitors, though average response rates can be a bit lower than in non-diabetic mendose-titration and adherence to instructions (timing, arousal) help improve results (systematic review in diabetes
