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The excessive expansion of adipose tissue in obesity disrupts adipokine secretion, fostering chronic low-grade inflammation and thereby contributing to the onset of metabolic disorders like obesity and T2DM

This finding suggests that DPP4 inhibitors, owing to their GLP-1-enhancing actions, may have a direct beneficial effect on cardiomyocyte function

Some patients experience frustrating plateaus despite continued medication use

The study, conducted using electronic health records from the TriNetX network between 2017 and 2024, excluded patients with prior neurodegenerative or cerebrovascular conditions and used propensity score matching to balance baseline characteristics

And Why Is It Important