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DSIP is a naturally occurring (endogenous) peptide that has been characterized in mammalian central nervous system tissue

Instead, it supports skin health internally, helping dry skin look healthier, smoother, and more balanced over time

The biggest known risks are retatrutide-driven GI side effects (nausea 38-43%, diarrhea 33-35%) and dysesthesia - an unusual skin tingling or burning sensation at higher doses

2003 Oct;66(8):14991503.

[37] PA may be considered as an end stage of autoimmune atrophic gastritis, a disease characterised by stomach atrophy and the presence of antibodies to parietal cells and intrinsic factor