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However, obesity specialists now estimate this figure may reach 20% in clinical practice
Similarly, a renal transporter is often referred to as a reabsorption transporter if it is expressed in the apical membrane, however, there are both uptake (reabsorption into the cell) and efflux (secretion into the tubular lumen) transporters in the apical membrane as in the basolateral membrane
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It has been shown to lead to better blood sugar control, improved hemoglobin levels, and greater weight loss in people with type 2 diabetes, compared with drugs that target GLP-1 alone
Gastrointestinal side effects were mostly mild to moderate and linked to TZP, occurring mainly during dose escalation
