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Overview Since their approval, the labels for anti-obesity GLP-1s (Zepbound, Wegovy, and Saxenda) have included warnings about the potential risk for suicidal ideation and instruct healthcare providers to monitor patients and discontinue use if they experience suicidal thoughts or behaviors
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Funding The research work in bibliographic references involving the author of this article has been partly funded by National Institutes of Health (NIH) grants R21MH82297, P30GM103328 and R56MH113828 as well as the ABMRF/The Foundation for Alcohol Research
These substances dangerously interact with certain medications, particularly nitrates, posing a risk of severe drops in blood pressure
2 Metabolism and regulation of BCAAs 2.1 Metabolic pathways of branched-chain amino acids As essential amino acids, branched-chain amino acids (BCAAs) must be obtained through dietary intake, primarily from protein-rich foods such as meat, dairy products, and legumes
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