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This represents about five half-lives, which is the standard timeframe for considering a medication essentially eliminated
Desbois-Mouthon C, Baron A, Blivet-Van Eggelpol MJ, Fartoux L, Venot C, Bladt F, et al
Muscle tissue needs a lot of energy
However, reduced side effects at lower doses may also reflect reduced therapeutic effect
113 Washington University School of Medicine
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