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Because retatrutide loses more total weight (up to ~24.2% in Phase 2), the absolute lean-mass loss can be larger even at a similar percentage
Mild flushing or warmth shortly after dosing
Adults with Obesity: Patients with a body mass index (BMI) of 30 or higher
Monitor your blood sugar levels regularly and report any unusual symptoms or side effects to your doctor
The one honest exception: TB-500 works partly by mass-action, so a higher local concentration in the brief window before it disperses is at least plausible
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