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This high degree of similarity suggests they arose from a relatively recent duplication event (Wickens et al., 2002
Current research also confirmed the possible interaction among AMPK/SIRT1, autophagy and NLRP3 inflammatory corpuscle pathway and their role in the potential anti-inflammatory neuroprotective effect of Liraglutide (Wang Z
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This has led to their licensed use for weight management in individuals with obesity or those who are overweight with weight-related comorbidities
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