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In 2014, the Stimulation Therapy for Apnea Reduction (STAR) trial found that, among patients with moderate-to-severe OSA and a body mass index (BMI) of less than 32 kg/m 2 , unilateral hypoglossal nerve stimulation led to a 68% reduction in OSA severity (based on AHI) at 12 months, and improvements in sleepiness scores [44]

FIGURE 9 Further, Dynamic Light Scattering (DLS), a widely used technique for determining the hydrodynamic size and size distribution of molecules in a sample by analyzing fluctuations in scattered light due to Brownian motion, was used to evaluate the hydrodynamic size distribution of 100 M SR18 under different solvent conditions

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