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In conclusion, GLP-1R activation triggers a series of complex physiological responses in pancreatic -cells that work together to increase insulin secretion, inhibit -cell apoptosis and stimulate proliferation, protect -cells and ultimately regulate blood glucose

This is related to factors such as insufficient gestation time, which prevents the placenta from accumulating and storing sufficient amounts of L-carnitine, lower oral food intake after birth, and a high metabolic rate in newborns (5)

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Mueller et al., 2019