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Glutathione is a simple sulphur compound composed of three amino acids (cysteine, glycine, and glutamic acid)
CstB exhibits no substrate preference between GSSH and CSSH The hypothesis that the C201-G202 dipeptide is a GSH mimic predicts that persulfide transfer between the LMW persulfide, e.g ., CSSH, GSSH, to the C201-G202 dipeptide creates the substrate for Fe(II)-dependent oxidation
This proactive approach prevents reflux from ever getting established
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