Liver issues are uncommon on GLP-1s, but contact your healthcare provider if you notice persistent fatigue beyond typical medication adjustment, upper right abdominal discomfort, dark urine or pale stools, yellowing of the skin or eyes, or nausea that worsens rather than improves over time
Instead, neuronal GLP-1Rs located outside the BBB primarily serve as peripheral targets for gut-derived or pharmacologically administered GLP-1 (Varin et al., 2019
Rather than ranting about how ridiculous these expectations are, well keep it short and say: this noise is unwelcome and uncalled for
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