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doi:10.1016/j.cmet.2016.02.005 Bartels RD, Kelly KM, Rothman AJ

After injection, semaglutide suppresses the hunger hormone (GLP-1) to delay natural responses to hunger

Morris MC, Tangney CC, Wang Y, et al

These data support inosine as a double-edged mediator: it can fuel and expand antitumor T-cell programs while AA-mediated signaling remains immunosuppressive, net effect depends on receptor context, costimulation, and route/dose of delivery

It remains unclear whether their use in a susceptible population, such as patients with both diabetes and underlying thyroid disease, might influence the risk of developing TED