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Consistent, weekly administration is crucial for maintaining steady drug levels and optimizing outcomes
It means: The medication has been studied in thousands of people in controlled trials
Side effects remain minimal for most individuals, allowing for smoother continuation of the treatment
The best-known studies were short-term endocrine studies in healthy adults, measuring GH, IGF-1, pharmacokinetics, and tolerability
The standard step requires a documented 90-day trial of metformin at a dose of at least 1 to 500 mg daily (or maximum tolerated dose), with lab evidence that A1C remains above the individualized goal
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